Description

Glucose 6-Arsenate is a specialized biochemical compound where an arsenate group is esterified to the 6-position of glucose. This molecule serves as a critical research tool and biochemical intermediate for studying metabolic pathways, particularly those involving phosphate analogs and enzyme inhibition. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic manufacturers engaged in advanced biochemical studies and assay development. The compound's unique structure makes it valuable for investigating arsenate toxicity mechanisms and glucose metabolism.

Application

• Biochemical Research: Used as a substrate analog in enzymatic studies, particularly for hexokinase and glucose-6-phosphate dehydrogenase, to investigate phosphate/arsenate competition.
• Metabolic Pathway Analysis: Serves as a tool to study aberrant glycolysis and pentose phosphate pathway activity under arsenate stress in cellular models.
• Toxicology Studies: Employed in research to understand the molecular mechanisms of arsenic toxicity and its interference with essential phosphate-based biological processes.
• Diagnostic Reagent Development: Acts as a key component in developing in-vitro diagnostic assays for metabolic enzyme function and activity.
• Pharmaceutical R&D: Utilized in drug discovery programs targeting metabolic enzymes or pathways affected by arsenate compounds.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related biochemical product manufacturing.

Basic Information

Product Name	Glucose 6-Arsenate
CAS No.	50410-18-9
Molecular Formula	C6H11AsO9
Molecular Weight	302.08 g/mol
Synonyms	D-Glucose 6-Arsenate; 6-O-Arsono-D-glucose; Arsonic acid, (6-O-D-glucopyranosyl)-; D-Glucose 6-(dihydrogen arsenate); Glucose-6-arsenate; 6-Arsonoglucose; (6-O-D-Glucopyranosyl)arsonic acid
EINECS	Contact for details

Quality Control

Our Glucose 6-Arsenate is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity analysis, NMR identification, and water content determination. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to ISO 9001 quality standards in our manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Arsenic Speciation	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.