Description

S-Glycolylglutathione is a specialized derivative of glutathione, a critical tripeptide involved in cellular redox balance and detoxification. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a potential metabolite and its involvement in advanced glycation end-product (AGE) pathways. It serves as a valuable reference standard and research chemical for scientists in pharmaceutical R&D, analytical chemistry, and life science research, particularly for studies on oxidative stress, metabolic disorders, and protein modification.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of drug metabolites and impurities in method development and validation.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to glutathione metabolism and detoxification pathways.
• Metabolite Studies: Serves as a key analyte in research investigating the formation and impact of advanced glycation end-products (AGEs) in diabetes and aging.
• Diagnostic Reagent Development: Utilized in the formulation of assay kits and reagents for detecting oxidative stress markers in clinical and research settings.
• Cell Culture & In Vitro Studies: Applied in media supplements or treatment solutions to study cellular responses to glycative and oxidative stress.
• Analytical Chemistry: Acts as a high-purity calibrant for advanced analytical techniques such as LC-MS/MS and HPLC in contract research organizations (CROs) and quality control labs.

Basic Information

Product Name	S-Glycolylglutathione
CAS No.	50409-85-3
Molecular Formula	C12H19N3O8S
Molecular Weight	365.36 g/mol
Synonyms	N-(N-L-γ-Glutamyl-L-cysteinyl)glycine, S-(Carboxymethyl)glutathione; Glycolylglutathione; S-Carboxymethylglutathione; Glutathione, S-(carboxymethyl)-; L-Glutathione, S-(carboxymethyl)-; NSC 113236; AGE Precursor
EINECS	Contact for details

Quality Control

Our S-Glycolylglutathione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.