Description

(3Z,8α,9R)-3,10-Didehydro-10,11-Dihydrocinchonan-6',9-Diol is a high-purity, structurally defined cinchona alkaloid derivative, serving as a critical chiral intermediate and reference standard in advanced organic synthesis. Its precise stereochemistry makes it invaluable for applications requiring high enantioselectivity, such as asymmetric catalysis and pharmaceutical development. This compound is essential for research and production laboratories in the pharmaceutical, agrochemical, and fine chemical sectors where chiral purity and structural integrity are paramount.

Application

• Asymmetric Synthesis Catalyst: Employed as a chiral ligand or organocatalyst in enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) with specific stereochemical requirements.
• Chiral Resolution Agent: Used for the separation of racemic mixtures via diastereomeric salt formation or as a chiral selector in chromatography.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, GC).
• Academic & Industrial Research: A valuable tool for studying reaction mechanisms, developing new catalytic systems, and exploring structure-activity relationships.
• Agrochemical Synthesis: Utilized in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.

Basic Information

Product Name	(3Z,8α,9R)-3,10-Didehydro-10,11-Dihydrocinchonan-6',9-Diol
CAS No.	5985-94-4
Molecular Formula	C19H22N2O2
Molecular Weight	310.39 g/mol
Synonyms	10,11-Dihydrocinchonidine; Dihydrocinchonidine; (8α,9R)-10,11-Dihydro-6'-hydroxycinchonan-9-ol; Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8α,9R)-; 3,10-Didehydro-10,11-dihydrocinchonan-6',9-diol; (3Z)-3,10-Didehydro-10,11-dihydrocinchonan-6',9-diol; A common intermediate of Cinchona Alkaloids.
EINECS	Contact for details

Quality Control

Every batch of (3Z,8α,9R)-3,10-Didehydro-10,11-Dihydrocinchonan-6',9-Diol is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.