Description

Synephrine Hydrochloride is a standardized, high-purity alkaloid derivative widely recognized for its role as a key active pharmaceutical ingredient (API) and dietary supplement component. This compound matters for its reliable performance in formulations requiring precise bioactivity and consistent quality. It is primarily needed by manufacturers in the pharmaceutical, nutraceutical, and research sectors for developing products targeting metabolic support and respiratory function.

Application

• Pharmaceutical Intermediates: Serves as a critical building block in the synthesis of advanced adrenergic agonists and decongestant medications.
• Dietary Supplements: A core ingredient in weight management and energy-boosting formulations due to its sympathomimetic properties.
• Reference Standards: Used in analytical laboratories as a certified reference material (CRM) for quality control and method validation in HPLC and GC analyses.
• Biochemical Research: Employed in preclinical studies to investigate adrenergic receptor activity, thermogenesis, and metabolic pathways.
• Veterinary Pharmaceuticals: Incorporated into formulations for animal health, particularly for respiratory support.

Basic Information

Product Name	Synephrine Hydrochloride
CAS No.	5985-28-4
Molecular Formula	C9H14ClNO2
Molecular Weight	203.66 g/mol
Synonyms	Oxedrine Hydrochloride; p-Synephrine Hydrochloride; Sympathomimetic B01; 4-[1-Hydroxy-2-(methylamino)ethyl]phenol Hydrochloride; (R,S)-Synephrine Hydrochloride; Bitter Orange Extract (Standardized); Citrus Aurantium Extract (Standardized); m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
EINECS	227-802-8

Quality Control

Our Synephrine Hydrochloride is manufactured under a GMP-compliant quality management system, ensuring batch-to-batch consistency for industrial and research applications. The product undergoes rigorous testing, including identity confirmation, purity assay, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.