Description

Hydrohydrastine Hydrobromide is a high-purity alkaloid salt derived from Hydrastis canadensis (Goldenseal). This compound is valued for its consistent quality and stability, making it a critical reference standard and intermediate in advanced research and development. It is primarily utilized by the pharmaceutical, biotechnology, and analytical chemistry sectors for method validation, pharmacological studies, and the synthesis of specialized derivatives.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and the validation of assay methods in quality control laboratories.
• Biochemical Research: Serves as a key intermediate or starting material in the synthesis of novel compounds for pharmacological evaluation.
• Analytical Chemistry: Employed as a certified standard in HPLC, LC-MS, and NMR for accurate quantification and identification.
• Pharmacological Studies: Utilized in in-vitro and in-vivo research to investigate biological activity and mechanism of action.
• Natural Product Isolation & Standardization: Acts as a marker compound for the standardization of Goldenseal extracts and related herbal products.

Basic Information

Product Name	Hydrohydrastine Hydrobromide
CAS No.	5985-05-7
Molecular Formula	C21H21NO5·HBr
Molecular Weight	448.31 g/mol
Synonyms	Hydrohydrastine HBr; Hydrohydrastine Hydrobromide Salt; 7,8-Dihydro-8β-hydroxyhydrastine Hydrobromide; Dihydrohydroberberine Hydrobromide; (13aS)-3,9,10-Trimethoxy-5,6,13,13a-tetrahydro-8H-dibenzo[a,g]quinolizine-2,11-diol hydrobromide; Hydrohydrastinium Bromide
EINECS	Contact for details

Quality Control

Our Hydrohydrastine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.