Description

n-Palmitoyl-D-Erythro-Sphinganine CAS NO 5966-29-0 is a high-purity, synthetic sphingolipid derivative, specifically a dihydroceramide, which serves as a critical intermediate in the biosynthesis of complex sphingolipids and ceramides. This compound is essential for researchers and manufacturers focused on lipid metabolism, cell signaling studies, and the development of advanced cosmetic and pharmaceutical formulations. It is particularly valuable for applications in biochemical research, dermatological active ingredient development, and high-end cosmetic science, where precise lipid structures are required to mimic biological functions.

Application

• Biochemical Research: A key precursor and standard for studying sphingolipid metabolism, ceramide synthesis pathways, and apoptosis.
• Cosmetic Science: Used in the development of advanced skincare products aimed at restoring the skin barrier, improving hydration, and providing anti-aging benefits.
• Pharmaceutical Development: Serves as a critical intermediate in the synthesis of more complex therapeutic agents targeting lipid-related disorders.
• Cell Biology Studies: Employed in cell culture and signaling experiments to investigate the role of ceramides in cellular processes.
• Lipidomics: Acts as a reference standard in mass spectrometry and chromatography for the identification and quantification of sphingolipids.
• Dermatological Actives: Incorporated into formulations for treating dry skin conditions, eczema, and psoriasis by supporting skin barrier integrity.

Basic Information

Product Name	n-Palmitoyl-D-Erythro-Sphinganine
CAS No.	5966-29-0
Molecular Formula	C₃₄H₆₇NO₃
Molecular Weight	537.90 g/mol
Synonyms	D-erythro-Dihydroceramide (C16:0); N-(1,3-Dihydroxy-2-hexadecanoylamino-4-octadecene)palmitamide; N-Palmitoylsphinganine; Dihydroceramide (d18:0/16:0); Cer(d18:0/16:0); N-Hexadecanoylsphinganine; (2S,3R)-2-Hexadecanamidooctadecane-1,3-diol; Sphinganine, N-palmitoyl-
EINECS	Contact for details

Quality Control

Our n-Palmitoyl-D-Erythro-Sphinganine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP guidelines where applicable to support research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.