Description

Cinchonine Sulfate is a high-purity salt of the cinchona alkaloid cinchonine, widely recognized for its chiral properties and biological activity. This compound is essential for applications requiring precise stereochemical control and serves as a critical intermediate in advanced organic synthesis. It is primarily utilized by the pharmaceutical, research, and fine chemical industries for chiral resolution, asymmetric catalysis, and as a reference standard.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers in pharmaceutical intermediates and fine chemicals.
• Asymmetric Synthesis Catalyst: Employed as a chiral ligand or catalyst in stereoselective chemical reactions.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Provides a certified standard for quality control and analytical method development in laboratories.
• Biochemical Research: Used in studies of biological membranes and ion channels due to its interaction with specific receptors.
• Fine Chemical Synthesis: A precursor for the manufacture of specialized chemicals and complex organic molecules.

Basic Information

Product Name	Cinchonine Sulfate
CAS No.	5949-16-6
Molecular Formula	C19H22N2O · H2SO4
Molecular Weight	384.46 g/mol (for free base C19H22N2O)
Synonyms	Cinchonine sulfate salt; (8S,9R)-Cinchonan-9-ol sulfate; Cinchonine hemisulfate; Cinchonine sulphate; Cinchonine hydrogen sulfate; Cinchonine, sulfate (1:1); NSC 199935
EINECS	227-698-8

Quality Control

Our Cinchonine Sulfate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation [α]20/D	-108° to -118° (c=1 in H2O)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.