Description

Cyclizine Lactate is a high-purity pharmaceutical salt form of the well-known antihistamine and antiemetic agent, Cyclizine. This compound is critical for ensuring the stability, solubility, and bioavailability of the active pharmaceutical ingredient in final dosage forms. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of injectable and oral medications targeting nausea, vomiting, and motion sickness. Our supply of Cyclizine Lactate CAS NO 5897-19-8 meets stringent quality standards for reliable integration into your production processes.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in antiemetic and antivertigo formulations.
• Injectable Solution Manufacturing: Key raw material for producing sterile injectable products, particularly where the lactate salt offers superior solubility.
• Oral Solid Dosage Forms: Used in the production of tablets and capsules for the treatment and prevention of motion sickness and postoperative nausea.
• Veterinary Pharmaceuticals: Application in veterinary medicine for managing nausea and vestibular disorders in animals.
• Research & Development (R&D): Serves as a critical reference standard and building block in pharmacological and pharmacokinetic studies.
• Controlled Drug Delivery Systems: Investigational use in developing sustained-release or targeted delivery mechanisms for improved therapeutic profiles.

Basic Information

Product Name	Cyclizine Lactate
CAS No.	5897-19-8
Molecular Formula	C18H22N2 • C3H6O3
Molecular Weight	388.47 g/mol
Synonyms	1-Diphenylmethyl-4-methylpiperazine lactate; Cyclizine (as lactate); Marzine Lactate; N-Benzhydryl-N'-methylpiperazine lactate; 1-(Diphenylmethyl)-4-methylpiperazine lactate; NSC-526046; Marazine; Valoid
EINECS	227-561-6

Quality Control

Our Cyclizine Lactate is manufactured and tested under a strict quality management system. Each batch is analyzed to ensure it meets high-purity specifications suitable for pharmaceutical applications, with testing typically including identification, assay, impurity profiling, and residual solvents. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all test results against predefined acceptance criteria. We support compliance with cGMP, ICH Q7 guidelines, and relevant pharmacopoeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.