Description

Cyclopentolate Hydrochloride is a potent anticholinergic agent used as a mydriatic and cycloplegic. This compound is critical for ophthalmic procedures requiring temporary paralysis of accommodation and pupil dilation. It is an essential active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers and compounding pharmacies for diagnostic and therapeutic applications.

Application

• Ophthalmic Solutions: Primary use in formulating eye drops for diagnostic cycloplegia and mydriasis.
• Pharmaceutical Intermediates: Serves as a key starting material or intermediate in synthesizing more complex therapeutic agents.
• Diagnostic Agent Manufacturing: Used in the production of diagnostic kits and solutions for eye examinations.
• Research & Development: Utilized in pharmacological studies related to muscarinic acetylcholine receptor antagonism.
• Veterinary Medicine: Applied in veterinary ophthalmic preparations for animal eye care.
• Reference Standard: Serves as a high-purity analytical standard for quality control laboratories.

Basic Information

Product Name	Cyclopentolate Hydrochloride
CAS No.	5870-29-1
Molecular Formula	C17H25NO3 • HCl
Molecular Weight	327.85 g/mol
Synonyms	Cyclopentolate HCl; 2-(Dimethylamino)ethyl 1-hydroxy-α-phenylcyclopentaneacetate hydrochloride; Cyclogyl; Cyclopentolatum; AK-Pentolate; Ocu-Pentolate; Cyclopentolate (Hydrochloride); (±)-Cyclopentolate hydrochloride
EINECS	227-524-0

Quality Control

Our Cyclopentolate Hydrochloride is manufactured under strict quality systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture and store under inert conditions if the container is opened frequently.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	-0.10° to +0.10° (c = 5 in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.