Description

Dicentrine Hydrochloride CAS NO 5742-03-0 is a high-purity alkaloid derivative, specifically the hydrochloride salt of dicentrine, valued for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate. Its primary commercial significance lies in enabling precise research, quality control, and development within the life sciences sector. This compound is essential for pharmaceutical R&D laboratories, analytical testing facilities, and manufacturers focused on neurological and cardiovascular therapeutic areas.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and purity testing of dicentrine and related alkaloids in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the synthesis and development of novel therapeutic agents.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate biological activity, particularly related to α-adrenergic receptor modulation.
• Analytical Chemistry: Acts as a calibration standard for chromatographic methods (HPLC, LC-MS) and spectroscopic analysis in method development and validation.
• Natural Product Isolation & Standardization: Used as a benchmark for the quantification of dicentrine in plant extracts and herbal formulations.

Basic Information

Product Name	Dicentrine Hydrochloride
CAS No.	5742-03-0
Molecular Formula	C20H21NO4·HCl
Molecular Weight	367.85 g/mol
Synonyms	Dicentrine HCl; 1,2,9,10-Tetramethoxy-6a,7-dihydro-4H-dibenzo[de,g]quinolin-11-ol Hydrochloride; (+)-Dicentrine Hydrochloride; Dicentrinium Chloride; NSC 407303; Glaziovine Precursor; Aporphine Alkaloid Hydrochloride
EINECS	Contact for details

Quality Control

Our Dicentrine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are supplied with every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.