Description

((1R,2R)-2-Amino-Cyclohexyl)-Methanol is a chiral amino alcohol derivative of cyclohexane, serving as a versatile and high-value building block in advanced organic synthesis. Its defined stereochemistry makes it a critical intermediate for constructing complex molecules with specific three-dimensional orientations. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where precise molecular architecture is paramount for activity and efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, neurological, and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand: Used to prepare chiral ligands for transition metal catalysts, enabling enantioselective reactions in fine chemical production.
• Peptidomimetic Chemistry: Incorporated into peptide backbones to create stable, bioactive analogs with improved pharmacological properties.
• Agrochemical Synthesis: Serves as a precursor for chiral herbicides, fungicides, and plant growth regulators.
• Material Science Monomer: Utilized in the synthesis of specialty polymers and resins with unique thermal or mechanical properties.
• Academic & Process R&D: A valuable reagent for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	((1R,2R)-2-Amino-Cyclohexyl)-Methanol
CAS No.	5691-15-6
Molecular Formula	C7H15NO
Molecular Weight	129.20 g/mol
Synonyms	(1R,2R)-2-(Aminomethyl)cyclohexanol; (1R,2R)-2-Aminomethylcyclohexanol; trans-2-(Aminomethyl)cyclohexanol; (1R,2R)-(-)-2-Aminomethylcyclohexanol; (1R,2R)-2-Hydroxymethylcyclohexylamine; (1R,2R)-1-Amino-2-(hydroxymethyl)cyclohexane; (1R,2R)-2-Amino-1-cyclohexylmethanol
EINECS	Contact for details

Quality Control

Our ((1R,2R)-2-Amino-Cyclohexyl)-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, chiral integrity, and consistency. We provide detailed Certificates of Analysis (COA) with data from HPLC, chiral chromatography, NMR, and other relevant techniques to support your quality assurance protocols and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.