Description

Pth-ε-Phenylthiocarbamyl-Dl-Lysine is a specialized derivative of the amino acid lysine, modified with a phenylthiocarbamyl (PTC) group at the epsilon position. This compound is a critical intermediate in peptide synthesis and sequencing methodologies, particularly in the Edman degradation process for N-terminal amino acid analysis. It is essential for research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in proteomics, analytical chemistry, and the production of high-purity peptide-based compounds.

Application

• Peptide Sequencing Reagent: Serves as a key intermediate or reference standard in Edman degradation for determining the amino acid sequence of peptides and proteins.
• Pharmaceutical Intermediate: Used in the research and development of novel peptide-based therapeutics and diagnostic agents.
• Analytical Chemistry Standard: Employed as a high-purity calibration standard in HPLC, LC-MS, and other chromatographic systems for method development and validation.
• Biochemical Research: Utilized in academic and industrial laboratories studying protein structure, function, and post-translational modifications.
• Proteomics: Applied in workflows for protein identification and characterization within complex biological samples.
• Fine Chemical Synthesis: Acts as a building block for the custom synthesis of more complex, labeled, or modified amino acid derivatives.

Basic Information

Product Name	Pth-ε-Phenylthiocarbamyl-Dl-Lysine
CAS No.	5657-26-1
Molecular Formula	C14H19N3O2S
Molecular Weight	293.39 g/mol
Synonyms	PTC-ε-Lysine; Nε-Phenylthiocarbamyl-L-lysine; Phenylthiocarbamyllysine; (S)-2,6-Diamino-N-(phenylcarbamothioyl)hexanamide; Edman Degradation Lysine Derivative; Lysine, N6-(phenylthiocarbamoyl)-; N6-(Phenylthiocarbamoyl)lysine
EINECS	Contact for details

Quality Control

Our Pth-ε-Phenylthiocarbamyl-Dl-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.