Description

1-Stearoyllysophosphatidylcholine is a single-chain phospholipid derivative, specifically a lysophospholipid, where a stearoyl fatty acid chain is esterified to the sn-1 position of the glycerol backbone. This compound serves as a critical intermediate and model lipid in advanced biochemical research and pharmaceutical development. It is essential for researchers and manufacturers in the life sciences, particularly for studying membrane biophysics, lipid metabolism, and as a precursor for synthesizing more complex phospholipids.

Application

• Biochemical Research: Used as a key reagent and standard in studies of lipid bilayer formation, membrane fluidity, and lipid-protein interactions.
• Pharmaceutical Excipient: Employed in the formulation of liposomal drug delivery systems to enhance stability and control the release of active pharmaceutical ingredients (APIs).
• Cell Culture & Media Supplement: Acts as a lipid source in serum-free media formulations to support the growth of specific cell lines.
• Diagnostic Reagent Manufacturing: A component in the production of reagents for clinical diagnostics, particularly in assays involving lipid metabolism.
• Cosmetic Formulations: Utilized in high-end skincare products for its emulsifying properties and potential skin-barrier repair functions.
• Synthetic Chemistry: Serves as a versatile building block for the chemical synthesis of other phospholipids and lipid conjugates.

Basic Information

Product Name	1-Stearoyllysophosphatidylcholine
CAS No.	5655-17-4
Molecular Formula	C26H54NO7P
Molecular Weight	523.68 g/mol
Synonyms	1-Stearoyl-sn-glycero-3-phosphocholine; LysoPC(18:0/0:0); L-α-Lysophosphatidylcholine, stearoyl; Lysostearin; 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-stearoyl; 18:0 Lyso PC; Stearoyl LPC
EINECS	227-100-5

Quality Control

Our 1-Stearoyllysophosphatidylcholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support compliance with cGMP and ISO 9001 standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized. For short-term use, vials may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (TLC)	Single major spot
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.