Description

(6S)-6-Deoxytetracycline CAS NO 5614-03-9 is a key intermediate in the synthesis of semi-synthetic tetracycline antibiotics. This compound is valued for its role in producing more potent and targeted antimicrobial agents with improved pharmacokinetic profiles. It is primarily required by pharmaceutical R&D laboratories and manufacturers specializing in advanced antibiotic production.

Application

• Pharmaceutical Intermediate: Critical starting material for the synthesis of second and third-generation tetracycline-class antibiotics.
• Antibiotic Research & Development: Used in medicinal chemistry programs to develop novel analogs with activity against resistant bacterial strains.
• Biochemical Research: Serves as a reference standard and tool compound for studying tetracycline biosynthesis and mode of action.
• Veterinary Pharmaceutical Manufacturing: Employed in the production of broad-spectrum antimicrobials for animal health.

Basic Information

Product Name	(6S)-6-Deoxytetracycline
CAS No.	5614-03-9
Molecular Formula	C₂₂H₂₄N₂O₇
Molecular Weight	428.44 g/mol
Synonyms	6-Deoxytetracycline; 6-DOTC; Desdimethylamino-6-deoxytetracycline; (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; NSC 529634; Antibiotic S 351; 6-Deoxy-5-hydroxytetracycline
EINECS	Contact for details

Quality Control

Our (6S)-6-Deoxytetracycline is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.