Description

Sanguinarine Chloride is a benzophenanthridine alkaloid salt known for its potent biological activity. This compound serves as a critical reference standard and active ingredient in research and development, offering significant value for its antimicrobial and anti-inflammatory properties. It is primarily utilized by the pharmaceutical, biotechnology, and academic research sectors for applications ranging from drug discovery to mechanistic studies.

Application

• Pharmaceutical research as a reference standard for analytical method development and validation.
• Active ingredient research for its potential antimicrobial and anti-inflammatory effects.
• Biochemical studies investigating its role as a selective STAT3 inhibitor and inducer of apoptosis.
• Development of oral care products, leveraging its historical use in anti-plaque and anti-gingivitis formulations.
• Use in veterinary medicine research for its antiparasitic properties.
• As a key intermediate in the synthesis of more complex benzophenanthridine alkaloids.
• Cell biology research for studying mechanisms of cell cycle arrest and necrosis.

Basic Information

Product Name	Sanguinarine Chloride
CAS No.	5578-73-4
Molecular Formula	C20H14ClNO4
Molecular Weight	367.78 g/mol
Synonyms	Sanguinarine chloride; Pseudochelerythrine chloride; 13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridinium chloride; Sanguinarinium chloride; Sanguinarine hydrochloride; Sanguiritrin (component); 1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium chloride
EINECS	226-940-9

Quality Control

Our Sanguinarine Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.