Description

Tauro-7,12-Dihydroxycholanic Acid is a conjugated bile acid derivative, specifically a taurine conjugate of a dihydroxylated cholanic acid. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a key intermediate in bile acid metabolism and its potential as a reference standard. It is primarily utilized by research institutions, pharmaceutical development labs, and fine chemical manufacturers focused on hepatology, gastroenterology, and metabolic disorder studies.

Application

• Biochemical Research: Used as a critical intermediate and reference standard in studies of bile acid synthesis, conjugation, and enterohepatic circulation.
• Pharmaceutical Development: Serves as a starting material or intermediate in the synthesis of novel therapeutic agents targeting liver and metabolic diseases.
• Diagnostic Reagents: Employed in the development and calibration of diagnostic assays and kits for measuring bile acid profiles in clinical samples.
• Metabolomics & Proteomics: Acts as a defined metabolite standard in mass spectrometry-based studies to understand metabolic pathways and disorders.
• Cell Culture & In Vitro Studies: Utilized in biological media to study the effects of specific bile acid conjugates on cell function and signaling.

Basic Information

Product Name	Tauro-7,12-Dihydroxycholanic Acid
CAS No.	5571-91-5
Molecular Formula	C₂₆H₄₅NO₇S
Molecular Weight	515.70 g/mol
Synonyms	7α,12α-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide; Tauro-7α,12α-Dihydroxy-5β-cholan-24-oate; Tauro-7α,12α-Dihydroxycholanate; Taurodeoxycholic Acid (common misnomer, verify isomer); Taurine Conjugate of 7,12-Dihydroxycholanic Acid; 5β-Cholan-24-oic Acid, 7α,12α-dihydroxy-, N-(2-sulfoethyl)-, Inner Salt; Tauro-Dihydroxycholanic Acid
EINECS	Contact for details

Quality Control

Our Tauro-7,12-Dihydroxycholanic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets high-purity research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent absorption of atmospheric moisture. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.