Description

H-Val-Oet Tos CAS NO 5366-33-6 is a high-purity, protected amino acid derivative, specifically the tosylate salt of H-Valine ethyl ester. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering reliable stereochemical integrity and reactivity. It is essential for research and production in the pharmaceutical and biotechnology sectors, particularly for the synthesis of peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptide-based drugs and therapeutic agents.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate valine residues with an ethyl ester protecting group.
• Protease Inhibitor Development: Serves as a precursor in the research and manufacturing of enzyme inhibitors targeting various proteases.
• Bioconjugation & Labeling: Utilized in the preparation of modified peptides for diagnostic and biochemical research applications.
• Academic & R&D: A valuable reagent for medicinal chemistry research, process development, and exploring new synthetic methodologies.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	H-Val-Oet Tos
CAS No.	5366-33-6
Molecular Formula	C15H23NO5S
Molecular Weight	329.41 g/mol
Synonyms	L-Valine, ethyl ester, 4-methylbenzenesulfonate; Ethyl L-valinate p-toluenesulfonate salt; H-Val-OEt·Tos; Valine ethyl ester tosylate; Ethyl valinate tosylate salt; (S)-2-Amino-3-methylbutanoic acid ethyl ester 4-methylbenzenesulfonate; Tosic acid salt of ethyl L-valinate
EINECS	226-348-4

Quality Control

Our H-Val-Oet Tos is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.