Description

Colchiceine, 7-Deacetoamino- is a key intermediate and derivative of the natural alkaloid colchicine. This compound is of significant interest in pharmaceutical research and development, particularly for its structural relevance to bioactive molecules. It serves as a critical building block for medicinal chemists and researchers in the life sciences sector, enabling the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of colchicine analogs and other bioactive alkaloids for drug discovery programs.
• Biochemical Research: Used as a reference standard and research tool in studies investigating tubulin polymerization inhibition and cellular mechanisms.
• Medicinal Chemistry: Serves as a scaffold for the development of new anti-inflammatory and anti-gout agent candidates.
• Academic Research: Employed in university and institutional labs for pharmacological and toxicological studies related to colchicine's effects.
• Process Development: Utilized in the optimization of synthetic routes for complex natural product derivatives in pilot-scale production.

Basic Information

Item	Details
Product Name	Colchiceine, 7-Deacetoamino-
CAS No.	5320-47-8
Molecular Formula	C20H21NO5
Molecular Weight	355.39 g/mol
Synonyms	7-Deacetylamino-10-demethylcolchiceine; 7-Deamino-7-oxocolchiceine; 3-Demethylcolchiceine; N-Deacetyl-N-formylcolchicine; Colchiceine Derivative; 7-Deacetamidocolchiceine; 10-Demethylcolchiceine
EINECS	Contact for details

Quality Control

Our Colchiceine, 7-Deacetoamino- is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets high-grade standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.