Description

(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-Didehydro-3β-Hydroxy-1-Methylaspidospermidine-3-Carboxylic Acid Methyl Ester CAS NO 5231-60-7 is a complex indole alkaloid derivative belonging to the aspidosperma class, characterized by its specific stereochemistry and functional groups. This compound serves as a critical advanced intermediate or reference standard in synthetic organic chemistry and pharmaceutical research. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutics or the study of natural product derivatives.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex bioactive molecules and potential drug candidates.
• Reference Standard: Used for analytical method development, validation, and quality control in research and production settings.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to explore new pharmacological properties.
• Natural Product Synthesis: Intermediate in the total or semi-synthesis of aspidosperma-type indole alkaloids and their analogs.
• Biochemical Research: Potential tool compound for investigating biological pathways and enzyme interactions related to alkaloid function.

Basic Information

Product Name	(2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-Didehydro-3β-Hydroxy-1-Methylaspidospermidine-3-Carboxylic Acid Methyl Ester
CAS No.	5231-60-7
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	Methyl (2β,5α,12β,19α)-4β-(acetyloxy)-6,7-didehydro-3β-hydroxy-1-methylaspidospermidine-3-carboxylate; 1-Methylaspidospermidine-3-carboxylic acid, 4-(acetyloxy)-6,7-didehydro-3-hydroxy-, methyl ester, (2β,5α,12β,19α)-; Tabersonine derivative; Vinca alkaloid intermediate; Aspidospermidine-3-carboxylic acid methyl ester derivative; 3-Carbomethoxy-1-methylaspidospermidine derivative
EINECS	Contact for details

Quality Control

Our (2β,5α,12β,19α)-4β-(Acetyloxy)-6,7-Didehydro-3β-Hydroxy-1-Methylaspidospermidine-3-Carboxylic Acid Methyl Ester is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing all test results are provided to ensure full traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.