Description

(3β,7R,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester is a high-purity, structurally complex oxindole alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical intermediate or reference standard for developing novel therapeutic agents, particularly those targeting neurological pathways. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of bioactive natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel central nervous system (CNS) active compounds and other bioactive molecules.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing and regulatory compliance.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological activity of corynoxan-based alkaloids.
• Academic Research: Serves as a substrate or template in studies investigating alkaloid biosynthesis, chemical reactivity, and novel synthetic methodologies.
• Biochemical Tool: Potential use in pharmacological assays to study receptor interactions and cellular signaling mechanisms.

Basic Information

Product Name	(3β,7R,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester
CAS No.	5171-42-6
Molecular Formula	C₂₁H₂₄N₂O₅
Molecular Weight	384.43 g/mol
Synonyms	9-Hydroxy-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester; Methyl (3β,7R,16E)-16,17-didehydro-9-hydroxy-17-methoxy-2-oxocorynoxan-16-carboxylate; Corynoxan-16-carboxylic acid derivative; Oxindole alkaloid intermediate; 16,17-Didehydrocorynoxan derivative
EINECS	Contact for details

Quality Control

Our (3β,7R,16E)-16,17-Didehydro-9-Hydroxy-17-Methoxy-2-Oxocorynoxan-16-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under inert atmosphere to preserve stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.