Description

n-Methylcoclaurine is a significant benzylisoquinoline alkaloid, a key intermediate in the biosynthesis of numerous pharmacologically active compounds. Its primary commercial value lies in its role as a versatile building block for research and development in medicinal chemistry and pharmacology. This product is essential for pharmaceutical R&D laboratories, biotechnology firms, and academic institutions focused on alkaloid synthesis, neuroscience, and cardiovascular research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex isoquinoline alkaloids and potential active pharmaceutical ingredients (APIs).
• Neuroscience Research: Used in studies investigating neurotransmitter pathways, receptor binding, and neurological mechanisms due to its structural similarity to endogenous alkaloids.
• Biochemical Standard: Serves as a reference standard or analytical standard for quality control and method development in phytochemical analysis.
• Medicinal Chemistry: Employed as a scaffold for the design and development of novel therapeutic agents targeting various disease pathways.
• Academic & Industrial R&D: Fundamental material for synthetic organic chemistry research, pathway elucidation, and process development.

Basic Information

Product Name	n-Methylcoclaurine
CAS No.	5096-70-8
Molecular Formula	C19H23NO4
Molecular Weight	329.39 g/mol
Synonyms	N-Methylcoclaurine; (+)-N-Methylcoclaurine; (S)-N-Methylcoclaurine; 6,7-Dimethoxy-1-[(4-hydroxy-3-methoxyphenyl)methyl]-2-methyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-[(4-hydroxy-3-methoxyphenyl)methyl]-2-methylisoquinoline; NSC 343647; Coclaurine, N-methyl-
EINECS	Contact for details

Quality Control

Our n-Methylcoclaurine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a desiccated environment away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.