Description

Annotine CAS NO 5096-59-3 is a high-purity alkaloid compound of significant interest in advanced research and development. This specialized chemical serves as a critical building block and reference standard for pharmaceutical and biochemical studies. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules and the investigation of natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate biological pathways and receptor interactions.
• Natural Product Chemistry: Acts as a model compound for the study, isolation, and structural modification of related alkaloids.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for method development, calibration, and quality control.
• Academic & Industrial R&D: Fundamental material for exploratory chemistry and the development of new synthetic methodologies in both academic and industrial settings.

Basic Information

Product Name	Annotine
CAS No.	5096-59-3
Molecular Formula	C16H19NO3
Molecular Weight	273.33 g/mol
Synonyms	Annotine; 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinoline; 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; NSC 407347; Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-
EINECS	225-805-2

Quality Control

Our Annotine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling, to meet the exacting standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.