Description

Chasmanine CAS NO 5066-78-4 is a diterpenoid alkaloid, a class of natural products known for their complex structures and significant biological activity. This high-purity compound is valued as a critical reference standard and a key intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical companies engaged in the synthesis of novel bioactive molecules and the quality control of related botanical extracts.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification, purity assessment, and quantification of chasmanine and related alkaloids in complex matrices via HPLC, LC-MS, or GC-MS.
• Biomedical Research: Used as a key intermediate or probe in pharmacological studies to investigate structure-activity relationships, metabolic pathways, and potential therapeutic applications of diterpenoid alkaloids.
• Natural Product Isolation & Synthesis: Acts as a benchmark compound for the isolation, purification, and structural confirmation of related alkaloids from plant sources, as well as a starting material or target in synthetic chemistry programs.
• Analytical Method Development: Employed in the development and validation of analytical methods for the detection and characterization of alkaloids in quality control laboratories for herbal medicines and dietary supplements.
• Chemical Biology Studies: Utilized as a tool compound to study biological mechanisms, enzyme interactions, and cellular signaling pathways influenced by diterpenoid alkaloids.

Basic Information

Product Name	Chasmanine
CAS No.	5066-78-4
Molecular Formula	C25H41NO6
Molecular Weight	451.60 g/mol
Synonyms	Chasmanine; (1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol; Delphatine; Isochasmanine; NSC 169854; Aconitane-7,8,14-triol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1α,6α,14α,16β)-
EINECS	Contact for details

Quality Control

Our Chasmanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all test results against established in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.