Description

Glycerol, [2-3H] is a tritium-labeled analog of glycerol, a fundamental biochemical building block. This labeled compound is essential for metabolic and pharmacokinetic tracer studies, enabling precise tracking of glycerol's fate in biological systems. It is a critical reagent for researchers in pharmaceutical development, biochemistry, and lipid metabolism, where understanding pathways and turnover rates is paramount.

Application

• Metabolic Tracer Studies: Used to investigate glycerol metabolism, gluconeogenesis, and triglyceride synthesis pathways in vivo and in vitro.
• Pharmacokinetics & Drug Metabolism (DMPK): Employed as a radiolabeled tracer to study the absorption, distribution, metabolism, and excretion (ADME) of glycerol-containing compounds.
• Lipid Biochemistry Research: Essential for tracing the incorporation of glycerol into complex lipids, phospholipids, and cell membranes.
• Enzymology Assays: Serves as a substrate for studying the activity of kinases, dehydrogenases, and other enzymes involved in glycerol metabolism.
• Diagnostic Agent Development: Used in the research and development of novel diagnostic imaging agents and probes.

Basic Information

Product Name	Glycerol, [2-3H]
CAS No.	5034-70-8
Molecular Formula	C3H53HO3
Molecular Weight	~94.09 g/mol (varies with specific activity)
Synonyms	1,2,3-Propanetriol, [2-3H]; [2-3H]Glycerol; Glycerin-2-t; Tritiated Glycerol (2-3H); 2-Tritio-1,2,3-propanetriol; DL-Glycerol-2-t; Radiolabeled Glycerol; Glycerol-t
EINECS	Contact for details

Quality Control

Every batch of Glycerol, [2-3H] is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data including radiochemical purity (by HPLC), specific activity, and chemical purity assessments. Certificates of Analysis (COA) detailing all specifications and test results are supplied with each shipment to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting under inert atmosphere to maintain optimal stability and specific activity.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR/NMR)	Conforms to structure
Specific Activity	Customizable (Ci/mmol or GBq/mmol)
Radiochemical Purity (HPLC)	≥ 97%
Chemical Purity (HPLC/GC)	≥ 98%
Solvent	Ethanol/Water or as specified
Concentration	1 mCi/mL (typical, customizable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.