Description

Napelline CAS NO 5008-52-6 is a diterpenoid alkaloid, a class of natural products known for their complex structures and significant biological activity. This compound is of primary interest for research and development within the pharmaceutical and life sciences sectors. It serves as a valuable reference standard and a key intermediate for investigating novel therapeutic agents, particularly for researchers focused on neuropharmacology and natural product chemistry.

Application

• Pharmaceutical Research: Used as a high-purity reference standard in analytical method development and quality control for drug discovery pipelines.
• Biochemical Studies: Employed as a pharmacological tool to study receptor interactions and signal transduction pathways in neurological research.
• Natural Product Isolation: Acts as a critical marker compound for the identification and standardization of plant extracts containing diterpenoid alkaloids.
• Academic Research: Serves as a starting material or intermediate for synthetic chemistry and structure-activity relationship (SAR) studies in university and institutional labs.
• Analytical Testing: Essential for calibrating instruments like HPLC and LC-MS in contract research organizations (CROs) and quality assurance labs.

Basic Information

Product Name	Napelline
CAS No.	5008-52-6
Molecular Formula	C22H33NO3
Molecular Weight	359.51 g/mol
Synonyms	Napelline; Lucaconine; 12-Epinapelline; (1α,6α,14α,16β)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-7,8,14-triol; Aconitane-7,8,14-triol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1α,6α,14α,16β)-; Lucaconitine
EINECS	Contact for details

Quality Control

Our Napelline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant standards for reference materials, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.