Description

Descinolone is a synthetic corticosteroid compound with significant anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for developing targeted therapeutic formulations that require precise biological activity. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development of topical and systemic treatments for dermatological and inflammatory conditions.

Application

• Pharmaceutical API: Serves as a key active ingredient in the formulation of corticosteroid-based medications.
• Topical Dermatological Preparations: Used in creams, ointments, and lotions for treating eczema, psoriasis, and other inflammatory skin disorders.
• Veterinary Medicine: Incorporated into anti-inflammatory treatments for animals.
• Biochemical Research: Employed as a reference standard and research tool in pharmacological studies of glucocorticoid receptor activity.
• Advanced Drug Delivery Systems: A candidate for encapsulation in liposomal or nanoparticle carriers for controlled release.

Basic Information

Product Name	Descinolone
CAS No.	595-52-8
Molecular Formula	C22H28O5
Molecular Weight	372.46 g/mol
Synonyms	9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-hydroxyprednisolone; Descinolone; Desoximetasone Impurity C; 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
EINECS	Contact for details

Quality Control

Our Descinolone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, related substances analysis, and residual solvent screening, to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.