Description

14-Alpha,17-Alpha,21-Trihydroxypregn-4-Ene-3,20-Dione is a synthetic steroid derivative with a complex hydroxylated pregnane structure. This compound serves as a critical intermediate in the synthesis of more complex steroid-based pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of specialized corticosteroid analogs and other bioactive steroid molecules.
• Research & Development: Used as a reference standard or starting material in medicinal chemistry research for studying structure-activity relationships (SAR) of steroid hormones.
• Fine Chemical Synthesis: Employed in the production of high-value, complex organic compounds for advanced material science and chemical biology applications.
• Biochemical Studies: Acts as a precursor or ligand in enzymatic studies and receptor binding assays to investigate steroid metabolism and signaling pathways.

Basic Information

Product Name	14-Alpha,17-Alpha,21-Trihydroxypregn-4-Ene-3,20-Dione
CAS No.	595-18-6
Molecular Formula	C₂₁H₃₀O₅
Molecular Weight	362.46 g/mol
Synonyms	14α,17α,21-Trihydroxypregn-4-ene-3,20-dione; 14α,17α,21-Trihydroxyprogesterone; 14α-Hydroxy-17α,21-dihydroxypregn-4-ene-3,20-dione; 14α-Hydroxydesoxycorticosterone; 14α-Hydroxy DOC; 14α,17α-Dihydroxy-21-hydroxypregn-4-ene-3,20-dione; Pregn-4-ene-3,20-dione, 14,17,21-trihydroxy-, (14α,17α)-
EINECS	Contact for details

Quality Control

Our 14-Alpha,17-Alpha,21-Trihydroxypregn-4-Ene-3,20-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and synthesis applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.