Description

8-Mercaptopurine is a sulfur-containing purine analog with significant biological activity. This compound is a critical building block and active pharmaceutical ingredient (API) in the synthesis of chemotherapeutic agents. It is primarily utilized by the pharmaceutical industry for the development and production of treatments for specific oncological conditions. Our supply ensures high purity and consistent quality for demanding research and manufacturing applications.

Application

• Pharmaceutical API: Serves as the active ingredient in chemotherapy drugs, particularly for the treatment of acute lymphoblastic leukemia (ALL).
• Biochemical Research: Used as a key reagent in studies involving purine metabolism, enzyme inhibition, and cell proliferation.
• Antimetabolite Synthesis: Acts as a fundamental precursor in the synthesis of various antimetabolite and immunosuppressive agents.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for drug testing and validation.
• Life Science Manufacturing: Incorporated into diagnostic kits and research-grade biochemicals for life science applications.

Basic Information

Product Name	8-Mercaptopurine
CAS No.	583-40-4
Molecular Formula	C5H4N4S
Molecular Weight	152.18 g/mol
Synonyms	6-Mercaptopurine (tautomer); 6-Thiohypoxanthine; 6-Thiopurine; 6-Hydroxypurine-6-thione; Purine-6-thiol; Leukerin; Purinethol; 6-MP; NSC-755; 1,7-Dihydro-6H-purine-6-thione
EINECS	209-513-6

Quality Control

Our 8-Mercaptopurine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided to guarantee traceability and compliance with relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere when appropriate for long-term stability.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.