Description

Synephrine is a naturally occurring alkaloid and sympathomimetic amine, structurally related to ephedrine and phenylephrine, with the CAS registry number 582-84-3. It serves as a key intermediate in pharmaceutical synthesis and a bioactive ingredient in dietary supplements, valued for its targeted physiological effects. This compound is essential for manufacturers in the pharmaceutical, nutraceutical, and research sectors requiring a reliable, high-purity building block.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of adrenergic agents and decongestants.
• Dietary Supplements: Used as a core ingredient in weight management and energy-boosting formulations for its purported thermogenic properties.
• Research & Development: Employed in biochemical and pharmacological studies to investigate adrenergic receptor activity and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical and supplement manufacturing.
• Cosmetic Applications: Incorporated into topical formulations for its potential vasoconstrictive effects.

Basic Information

Product Name	Synephrine
CAS No.	582-84-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	Oxedrine; p-Synephrine; Sympathol; p-Hydroxy-α-[(methylamino)methyl]benzyl alcohol; (±)-Synephrine; Bitter Orange Extract (primary alkaloid); Citrus aurantium extract (standardized); m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol (isomer)
EINECS	209-482-6

Quality Control

Our Synephrine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity data, residual solvent profiles, and identification confirmation. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we can support compliance with relevant pharmacopeial standards (e.g., USP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.