Description

(1S,5R)-6β,7β-Dihydroxy-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-One CAS NO 575-63-3 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex bioactive molecules, particularly in the development of tropane alkaloid derivatives and chiral building blocks. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those with tropane or nortropane skeletons.
• Asymmetric Synthesis: Serves as a valuable chiral building block or ligand precursor for catalytic asymmetric reactions.
• Medicinal Chemistry Research: Used in the research and development of new therapeutic agents targeting the central nervous system (CNS) and other areas.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	(1S,5R)-6β,7β-Dihydroxy-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-One
CAS No.	575-63-3
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	6β,7β-Dihydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-one; 8-Methyl-8-azabicyclo[3.2.1]octane-6β,7β-diol-3-one; Tropane-6β,7β-diol-3-one; Nortropane derivative; 3-Tropinone-6β,7β-diol; 8-Methylnortropinone-6β,7β-diol
EINECS	Contact for details

Quality Control

Our (1S,5R)-6β,7β-Dihydroxy-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.