Description

6-Mercaptopurine Riboside is a purine nucleoside analog and a key intermediate in the synthesis of biologically active compounds. Its primary value lies in its role as a precursor for the production of thiopurine drugs and in biochemical research, where it serves as a critical tool for studying nucleoside metabolism and enzyme inhibition. This compound is essential for pharmaceutical manufacturers and research institutions focused on oncology, immunology, and antiviral drug development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for thiopurine-based medications.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine salvage pathways and nucleoside metabolism.
• Oncology Research: Investigated for its potential antimetabolite activity in cell culture and preclinical studies targeting proliferative diseases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Antiviral Agent Development: Explored as a building block for novel nucleoside analogs with potential antiviral properties.

Basic Information

Product Name	6-Mercaptopurine Riboside
CAS No.	574-25-4
Molecular Formula	C10H12N4O4S
Molecular Weight	284.29 g/mol
Synonyms	6-Thioinosine; 6-MP Riboside; 6-Thioguanosine (related analog); Mercaptopurine Ribonucleoside; NSC-4911; 9-β-D-Ribofuranosyl-6-mercaptopurine; 6-MPR; Thioinosine
EINECS	209-363-5

Quality Control

Our 6-Mercaptopurine Riboside is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents. We can supply material suitable for research and development purposes, with specifications aligned with industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.