Description

Nandinine CAS NO 572-76-9 is a naturally occurring isoquinoline alkaloid, a key chemical entity of significant interest in advanced research and development. This compound serves as a crucial intermediate and reference standard for the synthesis and study of more complex bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity fine chemicals for use in pharmacological studies and as a building block for novel therapeutics.

Application

• Pharmaceutical Research & Development: As a reference standard and key intermediate in the synthesis of novel alkaloid-based drug candidates.
• Academic & Biochemical Studies: For investigating the biological activity, metabolic pathways, and structure-activity relationships (SAR) of isoquinoline alkaloids.
• Natural Product Isolation & Analysis: Used as a comparative standard in the isolation, identification, and quantification of related alkaloids from plant extracts.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the preparation of more complex, high-value specialty chemicals.
• Quality Control & Analytical Testing: Employed as a certified reference material (CRM) in HPLC, LC-MS, and other analytical methods to ensure accuracy and compliance.

Basic Information

Product Name	Nandinine
CAS No.	572-76-9
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.37 g/mol
Synonyms	Nandinin; (+)-Nandinine; (S)-Nandinine; 1,2,3,4-Tetrahydro-7-hydroxy-6-methoxy-1-[(4-hydroxyphenyl)methyl]-2-methylisoquinoline; Berbine, 7-hydroxy-6-methoxy-2-methyl-1-(4-hydroxybenzyl)-, (S)-; Nandazurine (related base)
EINECS	Contact for details

Quality Control

Our Nandinine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.