Description

(9R)-6'-Methoxycinchonan-9-Ol CAS NO 572-59-8 is a high-purity cinchona alkaloid derivative, a key chiral building block and ligand in asymmetric synthesis. Its primary commercial value lies in its role as a precursor to advanced catalysts and resolving agents, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemical control is critical.

Application

• Asymmetric Synthesis Catalyst Precursor: Serves as a vital intermediate in the synthesis of cinchona-based organocatalysts for enantioselective reactions.
• Chiral Resolution Agent: Used for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• Pharmaceutical Intermediate: A key chiral synthon in the development and production of active pharmaceutical ingredients (APIs), particularly for antimalarial and antiarrhythmic drugs.
• Ligand for Metal Complexes: Employed in the preparation of chiral ligands for transition metal catalysis.
• Research & Development: A standard compound in academic and industrial R&D for studying stereochemistry and developing new synthetic methodologies.
• Fine Chemical Synthesis: Utilized in the manufacture of high-value, complex organic molecules requiring specific stereochemistry.

Basic Information

Product Name	(9R)-6'-Methoxycinchonan-9-Ol
CAS No.	572-59-8
Molecular Formula	C₂₀H₂₄N₂O₂
Molecular Weight	324.42 g/mol
Synonyms	6'-Methoxycinchonan-9-ol; (R)-6'-Methoxycinchonan-9-ol; Cinchonan-9-ol, 6'-methoxy-, (9R)-; (9R)-6'-Methoxycinchonan-9-ol; (R)-6-Methoxycinchonan-9-ol; 6-Methoxycinchonan-9-ol (R)-; Dihydroquinine (impurity of); Quinotoxine (related compound); 572-59-8
EINECS	209-348-7

Quality Control

Every batch of (9R)-6'-Methoxycinchonan-9-Ol is produced under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and chiral purity. Our quality protocols are designed to support applications in GMP-aligned environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.