Description

11-Cis Retinal is a vital chromophore and the light-sensitive form of Vitamin A aldehyde essential for the visual cycle. This compound matters because it is the precise isomer that binds to opsin proteins in the retina to form functional visual pigments like rhodopsin, enabling phototransduction. Industries involved in advanced biochemical research, ophthalmology, and the synthesis of retinoid-based pharmaceuticals require this high-purity intermediate for studying vision mechanisms and developing related therapies.

Application

• Biochemical Research: Critical reagent for studying the molecular mechanisms of vision, phototransduction, and retinal protein interactions.
• Ophthalmology & Vision Science: Used in the reconstitution of visual pigments (e.g., rhodopsin) for in vitro studies and diagnostic assay development.
• Pharmaceutical Intermediate: Serves as a key synthetic precursor for novel retinoid-based drugs targeting retinal diseases.
• Nutraceutical Development: Employed in high-end research for formulating advanced eye health supplements.
• Academic & Industrial R&D: Essential for laboratories investigating retinoid biochemistry, signal transduction, and photoreceptor cell biology.
• Reference Standard: Used as a high-purity analytical standard in HPLC and LC-MS methods for quality control of retinoid products.

Basic Information

Product Name	11-Cis Retinal
CAS No.	564-87-4
Molecular Formula	C₂₀H₂₈O
Molecular Weight	284.44 g/mol
Synonyms	11-cis-Retinal; 11-cis-Retinaldehyde; (11Z)-Retinal; Vitamin A Aldehyde (11-cis-); 11-Z-Retinal; 11-cis-Vitamin A Aldehyde; all-trans-Retinal (isomer); β-Retinal (cis-)
EINECS	209-291-2

Quality Control

Our 11-Cis Retinal is produced and tested under stringent quality management protocols to ensure exceptional purity and batch-to-batch consistency, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, isomer specificity, and impurity profiles as determined by advanced chromatographic methods. Our quality commitment aligns with the rigorous standards expected in pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures of -20°C or below for long-term stability. This product is light-sensitive and easily oxidized; avoid repeated warming to room temperature and minimize exposure to air during handling.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference retention time
Purity (HPLC)	≥ 95% (11-cis isomer)
Isomeric Purity	Reported (typically ≥98% 11-cis by HPLC)
Related Substances (HPLC)	All-trans Retinal and other isomers: ≤ 2.0% total
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.