Description

(8Alpha)-12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione is a complex ergot alkaloid derivative, a class of compounds known for their intricate molecular architecture and significant biological activity. This compound is valued as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily required by R&D laboratories and fine chemical manufacturers focused on neuroscience, cardiovascular research, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel ergot-based therapeutics.
• Biochemical Research: Used as a reference standard and tool compound in studies of serotonin and dopamine receptor interactions.
• Reference Material: Essential for analytical method development, validation, and quality control in pharmaceutical analysis.
• Neuroscience Research: Investigated for its potential pharmacological effects on neurological pathways and vascular tone.
• Academic Research: Employed in university and institutional labs for studies in medicinal chemistry and natural product synthesis.

Basic Information

Product Name	(8Alpha)-12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione
CAS No.	564-37-4
Molecular Formula	C32H41N5O5
Molecular Weight	575.70 g/mol
Synonyms	12'-Hydroxy-2',5'-diisopropylergotaman-3',6',18-trione; Dihydroergocristine impurity; 6,18-Secoergoline derivative; 8α-Hydroxy-2',5'α-diisopropylergotaman-3',6',18-trione; Ergot alkaloid derivative (C32H41N5O5); 12'-Hydroxy-α-dihydroergocristine-related compound; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (8Alpha)-12'-Hydroxy-2',5'α-Diisopropylergotaman-3',6',18-Trione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.