Description

Ergocornine is a naturally occurring ergot alkaloid of significant interest in pharmaceutical research and development. This compound serves as a crucial intermediate and reference standard for the synthesis and analysis of more complex ergoline derivatives. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of central nervous system agents and for analytical method validation.

Application

• Pharmaceutical Reference Standard: Used as a high-purity calibrant in analytical methods (HPLC, LC-MS) for quality control of ergot alkaloid-based drugs and natural products.
• Biochemical Research: Employed in studies investigating the mechanism of action, receptor binding, and metabolic pathways of ergot alkaloids.
• Chemical Synthesis: Acts as a key chiral building block or intermediate in the semi-synthesis of novel ergoline compounds with potential therapeutic applications.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and educational purposes concerning natural product chemistry.

Basic Information

Product Name	Ergocornine
CAS No.	564-36-3
Molecular Formula	C31H39N5O5
Molecular Weight	561.67 g/mol
Synonyms	Ergocornine; Dihydroergocornine; 12'-Hydroxy-2',5'-bis(1-methylethyl)ergotaman-3',6',18-trione; (5'α)-Ergoline-8-carboxamide, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-3',6',18-trione; Ergotaman-3',6',18-trione, 12'-hydroxy-2',5'-bis(1-methylethyl)-, (5'α)-; NSC 524759
EINECS	Contact for details

Quality Control

Our Ergocornine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced chromatographic methods. We are committed to meeting the stringent requirements of the global research and pharmaceutical development sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.