Description

Doxycycline CAS NO 564-25-0 is a broad-spectrum, second-generation tetracycline antibiotic. It is valued for its high potency, excellent bioavailability, and effectiveness against a wide range of gram-positive and gram-negative bacteria, as well as atypical pathogens. This makes it a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical and veterinary medicine industries, where it is formulated into capsules, tablets, and injectables.

Application

• Human Pharmaceutical Formulations: Primary API for oral and intravenous antibiotics used to treat respiratory infections, Lyme disease, acne, and malaria prophylaxis.
• Veterinary Medicine: Key ingredient in medicated feeds, powders, and injectables for treating bacterial infections in livestock, poultry, and companion animals.
• Research & Development: Used as a biochemical tool in microbiological and pharmacological research to study bacterial protein synthesis inhibition.
• Aquaculture: Employed in the treatment and prevention of bacterial diseases in farmed fish and shellfish.
• Reference Standard: Serves as a high-purity analytical standard for quality control testing in pharmaceutical laboratories.

Basic Information

Product Name	Doxycycline
CAS No.	564-25-0
Molecular Formula	C₂₂H₂₄N₂O₈
Molecular Weight	444.43 g/mol
Synonyms	Doxycycline Hydate; Doxycycline Monohydrate; Vibramycin; Doxy 100; GS 3065; (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate; α-6-Deoxy-5-oxytetracycline
EINECS	209-271-1

Quality Control

Our Doxycycline is manufactured and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, purity, and potency. A Certificate of Analysis (COA) documenting results for assay, related substances, residual solvents, and microbiological purity is provided to ensure full traceability and compliance with cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a low-humidity environment to maintain stability and potency.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	1.5% - 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbiological Purity	Total aerobic microbial count ≤ 1000 cfu/g Total combined yeasts/molds ≤ 100 cfu/g Absence of E. coli, Salmonella

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.