Description

(5α,11R,13β,19α)-1,2-Didehydrocrinan-11-Ol is a high-purity, stereochemically defined alkaloid compound of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and intermediate for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on alkaloid chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel therapeutic agents, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate alkaloid frameworks and natural product analogs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new bioactive compounds derived from the crinane skeleton.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing related alkaloids.
• Biochemical Research: Used as a tool compound to study biological pathways and receptor interactions associated with alkaloid structures.

Basic Information

Product Name	(5α,11R,13β,19α)-1,2-Didehydrocrinan-11-Ol
CAS No.	561-19-3
Molecular Formula	C16H19NO2
Molecular Weight	257.33 g/mol
Synonyms	1,2-Didehydrocrinan-11-ol; Crinan-11-ol, 1,2-didehydro-; 11-Hydroxy-1,2-didehydrocrinane; (5α,11R,13β,19α)-1,2-Didehydrocrinan-11-ol; 1,2-Didehydrocrinan-11β-ol; Lycorine derivative; Amaryllidaceae alkaloid intermediate
EINECS	Contact for details

Quality Control

Our (5α,11R,13β,19α)-1,2-Didehydrocrinan-11-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and chemical composition. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Optical Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.