Description

4α,9-Epoxycevane-3β,4,7α,14,15α,16β,20-Heptol 7-Acetate 15-[(R)-2-Methylbutanoate] is a complex diterpenoid alkaloid derivative, a high-purity reference standard critical for advanced chemical research and development. Its intricate polycyclic structure makes it a valuable intermediate for synthesizing novel bioactive compounds and for use as an analytical standard. This compound is primarily required by research institutions and pharmaceutical development laboratories focused on natural product chemistry, medicinal chemistry, and pharmacology.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.
• Medicinal Chemistry Research: Serves as a key intermediate or precursor in the synthesis of novel drug candidates, particularly those exploring diterpenoid alkaloid scaffolds for biological activity.
• Natural Product Isolation & Analysis: Acts as a critical standard for the identification, quantification, and characterization of related alkaloids in complex plant extracts and biological matrices.
• Biochemical Research: Utilized in studies investigating structure-activity relationships (SAR) and the mechanism of action of cevane-type alkaloids.
• Academic & Institutional Research: Employed in university and government laboratories for fundamental research in organic synthesis and phytochemistry.

Basic Information

Product Name	4α,9-Epoxycevane-3β,4,7α,14,15α,16β,20-Heptol 7-Acetate 15-[(R)-2-Methylbutanoate]
CAS No.	560-49-6
Molecular Formula	C32H48O10
Molecular Weight	592.72 g/mol
Synonyms	15-[(2R)-2-Methylbutanoyloxy]-3,4,14,16,20-pentahydroxy-7-acetyloxy-4,9-epoxycevan-11-one; 7-Acetyl-15-(2-methylbutyryl)protoverine; Protoverine 7-acetate 15-(2-methylbutyrate); Veratramine derivative; Cevane alkaloid ester; (3β,4β,7α,14α,15α,16β)-4,9-Epoxycevane-3,4,7,14,15,16,20-heptol 7-acetate 15-(2-methylbutanoate); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4α,9-Epoxycevane-3β,4,7α,14,15α,16β,20-Heptol 7-Acetate 15-[(R)-2-Methylbutanoate] is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing desiccated at -20°C. This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥95.0% (Area %)
Water Content (KF)	≤5.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.