Description

(2R,5R)-Aspidofractinine-1,3β-Dicarboxylic Acid Dimethyl Ester is a high-purity, chiral alkaloid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for pharmaceutical research, enabling the development of novel therapeutic agents with specific stereochemistry. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential active pharmaceutical ingredients (APIs), particularly for alkaloid-based drug candidates.
• Asymmetric Synthesis: Utilized as a stereochemically defined building block in catalytic asymmetric reactions to construct complex natural product analogs.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in the discovery of new bioactive molecules.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.
• Academic Research: Employed in university and institutional labs for studying synthetic methodologies and alkaloid chemistry.

Basic Information

Product Name	(2R,5R)-Aspidofractinine-1,3β-Dicarboxylic Acid Dimethyl Ester
CAS No.	559-52-4
Molecular Formula	C21H26N2O4
Molecular Weight	370.45 g/mol
Synonyms	Dimethyl (2R,5R)-aspidofractinine-1,3β-dicarboxylate; Aspidofractinine-1,3β-dicarboxylic acid dimethyl ester; 1,3β-Dicarbomethoxyaspidofractinine; (1R,3S,5R,19R)-1,3-Dicarbomethoxyaspidofractinine; Kopsinine derivative; Alkaloid K ester
EINECS	Contact for details

Quality Control

Our (2R,5R)-Aspidofractinine-1,3β-Dicarboxylic Acid Dimethyl Ester is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.