Description

Trimethobenzamide Hydrochloride is a high-purity pharmaceutical active ingredient (API) and a potent antiemetic agent. It is critical for the formulation of medications designed to prevent and treat severe nausea and vomiting. This compound is essential for pharmaceutical manufacturers and research institutions developing therapeutic solutions in neurology and gastroenterology.

Application

• Pharmaceutical API: Primary active ingredient in prescription antiemetic medications.
• Neurological Research: Used in studies related to the chemoreceptor trigger zone (CTZ) and dopamine receptor antagonism.
• Formulation Development: Serves as a key component in the R&D of tablets, capsules, and injectable solutions.
• Clinical Trial Materials: Supplied as a reference standard or raw material for clinical studies.
• Generic Drug Manufacturing: Sourced for the production of generic antiemetic drugs.
• Veterinary Pharmaceuticals: Potential application in veterinary medicine for managing nausea in animals.

Basic Information

Product Name	Trimethobenzamide Hydrochloride
CAS No.	554-92-7
Molecular Formula	C21H28ClN3O5
Molecular Weight	437.92 g/mol
Synonyms	Trimethobenzamide HCl; Tigan (brand name); N-[(4-(2-Dimethylaminoethoxy)phenyl)methyl]-3,4,5-trimethoxybenzamide hydrochloride; Benzamide, N-[[4-[2-(dimethylamino)ethoxy]phenyl]methyl]-3,4,5-trimethoxy-, hydrochloride; Ro 2-9578; NSC-106572; Trimethobenzamidum Hydrochloricum
EINECS	209-075-9

Quality Control

Our Trimethobenzamide Hydrochloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent purity and identity criteria, including compliance with relevant pharmacopeial standards (e.g., USP). A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.