Description

Supinine CAS NO 551-58-6 is a naturally occurring pyrrolizidine alkaloid, a class of compounds known for their diverse biological activities. This high-purity chemical intermediate is critical for research and development in pharmaceutical discovery and advanced organic synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and studying biochemical pathways.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Biochemical Research: Used as a tool compound in pharmacological studies to investigate receptor interactions, enzyme inhibition, and cellular signaling mechanisms related to pyrrolizidine alkaloids.
• Organic Synthesis: Acts as a sophisticated chiral building block for the total synthesis of complex natural products and other biologically active molecules.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) in analytical laboratories for method development, calibration, and quality control testing, especially in herbal medicine and toxicology.
• Academic Research: Utilized in university and institutional labs for fundamental chemical and biological research, contributing to publications and the advancement of scientific knowledge.

Basic Information

Product Name	Supinine
CAS No.	551-58-6
Molecular Formula	C15H25NO5
Molecular Weight	299.36 g/mol
Synonyms	Supinine; (1R,2R,7aR)-1,2,7,7a-Tetrahydro-1-hydroxy-6H-pyrrolizin-2-ylmethyl (2S)-2-hydroxy-2-(1-hydroxyethyl)butanoate; 12-Hydroxyretronecine 2-methylbutanoate; Supinine alkaloid
EINECS	Contact for details

Quality Control

Our Supinine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC and NMR. We adhere to cGMP principles where applicable to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.