Description

Protostephanine is a naturally occurring isoquinoline alkaloid with a complex tetracyclic structure, identified by CAS NO 549-28-0. This compound serves as a critical reference standard and a valuable pharmacological research intermediate for studying neurological pathways and potential therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of high-purity fine chemicals.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of alkaloid-based drugs and natural products in quality control laboratories.
• Neuroscience Research: Acts as a key biochemical tool for investigating receptor interactions and studying the biosynthesis of related alkaloids.
• Organic Synthesis Intermediate: Serves as a sophisticated starting material or building block for the synthesis of novel, complex molecules in medicinal chemistry.
• Analytical Method Development: Employed in developing and validating chromatographic methods (HPLC, LC-MS) for alkaloid detection and separation.
• Natural Product Isolation & Study: Used as a benchmark compound in the isolation, identification, and activity screening of plant-derived extracts.

Basic Information

Product Name	Protostephanine
CAS No.	549-28-0
Molecular Formula	C18H19NO3
Molecular Weight	297.35 g/mol
Synonyms	Protostephanine; 16,17-Dimethoxy-4-methyl-15-azahexacyclo[10.7.1.0²,¹⁰.0³,⁸.0¹³,¹⁷.0¹⁴,¹⁹]icosa-1(19),2,4,6,8,10,12,14,16-nonaen-18-ol; Stephania alkaloid
EINECS	Contact for details

Quality Control

Our Protostephanine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by advanced analytical techniques including HPLC and NMR. We adhere to relevant GMP guidelines for research-grade chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.