Description

Droperidol CAS NO 548-73-2 is a potent butyrophenone derivative belonging to the class of neuroleptic agents. It is a critical active pharmaceutical ingredient (API) valued for its strong antiemetic and tranquilizing properties. This compound is essential for manufacturers in the pharmaceutical industry, particularly for the formulation of injectable solutions used in clinical and surgical settings.

Application

• Primary Pharmaceutical Ingredient: Manufacture of injectable formulations for the prevention and treatment of postoperative nausea and vomiting (PONV).
• Neuroleptic Agent: Used in the management of acute agitation and delirium in hospital emergency and intensive care settings.
• Anesthesia Adjunct: Employed as a premedication or adjunct to anesthesia to provide sedation and reduce perioperative complications.
• Research Chemical: Serves as a reference standard and key intermediate in pharmacological and neurochemical research studies.
• Veterinary Medicine: Application in veterinary practice for sedation and antiemetic purposes in animals.

Basic Information

Product Name	Droperidol
CAS No.	548-73-2
Molecular Formula	C22H22FN3O2
Molecular Weight	379.43 g/mol
Synonyms	1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-2H-benzimidazol-2-one; Dehydrobenzperidol; Dridol; Droperidolum; Inapsin; Inapsine; R-4749; Sintodian
EINECS	208-955-1

Quality Control

Our Droperidol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including compliance with relevant pharmacopeial monographs. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee identity, purity, and potency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on dried basis)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.