Description

Oxyacanthine is a bioactive benzylisoquinoline alkaloid naturally found in plants of the Berberidaceae family, such as *Berberis vulgaris*. This compound serves as a crucial reference standard and a key intermediate in the research and development of novel pharmaceutical agents. Its primary value lies in its role for analytical and pharmacological studies, particularly in the investigation of anti-inflammatory, antimicrobial, and cardiovascular activities. Industries requiring high-purity natural product standards, including pharmaceutical R&D, academic research, and nutraceutical development, are the primary users of this material.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of herbal extracts and finished products in quality control laboratories.
• Biochemical Research: Serves as a key intermediate or inhibitor in studies exploring enzyme interactions, receptor binding assays, and metabolic pathway analysis.
• Natural Product Isolation & Synthesis: Acts as a benchmark compound for the isolation, purification, and structural elucidation of related alkaloids in phytochemistry.
• Pharmacological Screening: Employed in in vitro and in vivo studies to evaluate potential therapeutic effects, including anti-hypertensive and anti-arrhythmic activities.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) for the detection of alkaloids in complex matrices.

Basic Information

Item	Details
Product Name	Oxyacanthine
CAS No.	548-40-3
Molecular Formula	C37H40N2O6
Molecular Weight	608.73 g/mol
Synonyms	Oxyacanthine; (1S)-6,6',7-Trimethoxy-2-methyl-1-[(1S)-1,2,3,4-tetrahydro-6-methoxy-1-[(3,4,5-trimethoxyphenyl)methyl]-2-methyl-7-isoquinolinyl]-2(1H)-isoquinolinone; Oxycanthine; 7-O-Methylisothalicberine; NSC 350008; UNII-0WZ5Q8N61I
EINECS	Contact for details

Quality Control

Our Oxyacanthine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for research and reference standard applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting results for key parameters including assay, related substances, and residual solvents. We support compliance with various pharmacopeial and industry standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.