Description

Mevaldic Acid is a key biochemical intermediate in the mevalonate pathway, essential for the biosynthesis of isoprenoids and sterols. Its high purity and consistent quality are critical for ensuring reliable results in research and development, particularly in metabolic studies and pharmaceutical synthesis. This compound is primarily utilized by researchers in biochemistry, medicinal chemistry, and by manufacturers in the life sciences sector for applications ranging from enzymatic assays to the development of novel therapeutic agents.

Application

• Biochemical Research: As a vital intermediate in the mevalonate pathway for studying isoprenoid biosynthesis and cholesterol metabolism.
• Enzyme Substrate: Used in enzymatic assays to study the activity and kinetics of enzymes like HMG-CoA reductase.
• Pharmaceutical Development: Serves as a building block or reference standard in the synthesis and research of statins and other lipid-regulating drugs.
• Metabolic Pathway Analysis: Employed in cell culture and in vitro studies to trace and manipulate metabolic fluxes.
• Academic & Industrial R&D: A fundamental reagent for universities, contract research organizations (CROs), and biotech companies exploring metabolic diseases.
• Reference Standard: Used for quality control and calibration in analytical laboratories for accurate quantification in complex matrices.

Basic Information

Product Name	Mevaldic Acid
CAS No.	541-07-1
Molecular Formula	C6H10O4
Molecular Weight	146.14 g/mol
Synonyms	3-Hydroxy-3-methyl-5-oxopentanoic acid; 3-Hydroxy-3-methylglutaric semialdehyde; 3-Methyl-3-hydroxy-5-oxovaleric acid; β-Hydroxy-β-methylglutaric acid semialdehyde; Mevaldic acid (sodium salt); Mevalonate semialdehyde; 5-Oxo-3-hydroxy-3-methylpentanoic acid
EINECS	208-768-3

Quality Control

Every batch of Mevaldic Acid is produced and tested under a strict quality management system to ensure it meets the high standards required for research and development. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment aligns with the needs of cGMP-compliant research environments, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Ensure the storage area is well-ventilated and separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.