Description

Metanicotine CAS NO 538-79-4 is a synthetic alkaloid and a structural analog of nicotine, offering a valuable chemical scaffold for research and development. This compound is of significant interest in the fields of medicinal chemistry and pharmacology for its potential as a lead structure in the design of novel bioactive molecules. It serves as a critical intermediate and reference standard for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel nicotinic acetylcholine receptor (nAChR) ligands and other pharmacologically active compounds.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development, validation, and calibration in HPLC, GC, and LC-MS analyses.
• Medicinal Chemistry Studies: Employed in structure-activity relationship (SAR) studies to explore modifications of the nicotine backbone for potential therapeutic applications.
• Agrochemical Research: Investigated as a precursor or model compound in the development of new insecticides and pesticides that target specific neurological pathways.
• Biochemical Research: Utilized in in vitro and in vivo studies to understand the binding interactions and metabolic pathways of nicotine analogs.
• Chemical Synthesis: Serves as a versatile building block for organic synthesis, enabling the creation of complex heterocyclic compounds for various industrial applications.

Basic Information

Product Name	Metanicotine
CAS No.	538-79-4
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	3-(1-Methyl-2-pyrrolidinyl)pyridine; N-Methylmyosmine; Dihydrometanicotine; 1-Methyl-2-(3-pyridyl)pyrrolidine; Metanicotine base; Nicotine Impurity C; Nicotine analog; Nicotine derivative
EINECS	208-698-8

Quality Control

Every batch of Metanicotine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and industrial applications. A Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents is supplied with each shipment. Our quality protocols are designed to support compliance with global regulatory standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its nature of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.