Description

Tropacocaine CAS NO 537-26-8 is a naturally occurring tropane alkaloid and a structural analog of cocaine. This compound is of significant interest in pharmaceutical research and forensic science due to its unique pharmacological profile and role as a reference standard. It serves as a critical intermediate and analytical standard for researchers and quality control laboratories. Key industries that utilize this specialty chemical include pharmaceutical development, forensic toxicology, and academic research institutions focused on neurochemistry and alkaloid studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the calibration of analytical instruments and validation of testing methods in drug development and quality control.
• Forensic Analysis: Serves as a critical comparative standard in forensic toxicology for the identification and quantification of controlled substances and their metabolites.
• Biochemical Research: Employed in neuroscience and pharmacological studies to investigate the structure-activity relationships (SAR) of tropane alkaloids and their interactions with neurotransmitter systems.
• Chemical Synthesis: Acts as a key intermediate or starting material in the organic synthesis of novel compounds for medicinal chemistry research.
• Academic & Educational Use: Provided to universities and research institutes for instructional purposes in advanced chemistry and pharmacology courses.
• Method Development: Utilized by analytical laboratories to develop and optimize chromatographic (HPLC, GC) and spectroscopic methods for alkaloid analysis.

Basic Information

Product Name	Tropacocaine
CAS No.	537-26-8
Molecular Formula	C15H19NO2
Molecular Weight	245.32 g/mol
Synonyms	3β-Benzoyloxytropane; Tropacaine; Benzoylpseudotropine; NSC 406042; ψ-Tropine benzoate; 8-Methyl-8-azabicyclo[3.2.1]octan-3β-yl benzoate; Tropan-3β-ol benzoate
EINECS	Contact for details

Quality Control

Our Tropacocaine is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including identification by IR spectroscopy and purity assessment by HPLC. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters. We adhere to relevant industry standards to support our clients in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	49 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.