Description

1,1'-Carbonyldiimidazole (CDI) is a versatile and highly reactive coupling agent widely used in organic synthesis for the formation of amides, esters, and carbonates. Its primary value lies in its ability to facilitate reactions under mild conditions without generating acidic by-products, making it a superior alternative to traditional reagents like acid chlorides. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and peptide synthesis industries, where high-purity intermediates are critical.

Application

• Peptide Synthesis: A key reagent for coupling amino acids without racemization.
• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for amide and ester bond formation.
• Agrochemical Production: Employed in the manufacture of herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Serves as a monomer or coupling agent in the production of polycarbonates, polyurethanes, and other specialty polymers.
• Carboxyl Activation: Activates carboxylic acids for subsequent nucleophilic attack by amines or alcohols.
• Bioconjugation: Useful for labeling and modifying biomolecules in diagnostic and research applications.
• Chemical Reagent: A fundamental tool in research laboratories for a wide range of organic transformations.

Basic Information

Product Name	1,1'-Carbonyldiimidazole
CAS No.	530-62-1
Molecular Formula	C7H6N4O
Molecular Weight	162.15 g/mol
Synonyms	CDI; Carbonyldiimidazole; N,N'-Carbonyldiimidazole; 1,1'-Carbonyldi-1H-imidazole; Imidazole, 1,1'-carbonylbis-; NSC 93619; Carbonyl diimidazole
EINECS	208-487-9

Quality Control

Our 1,1'-Carbonyldiimidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR spectroscopy, to ensure it meets high-purity standards suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Melting Point	115 - 120 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.