Description

(5S,11S)-5,6,11,12-Tetrahydro-2,3,8,9-Tetramethoxy-5,11-Epiminodibenzo[A,E]Cyclooctene CAS NO 529-79-3 is a complex, chiral tetrahydroisoquinoline alkaloid derivative with a rigid, bridged cyclooctene structure. This compound is of significant value as a sophisticated pharmaceutical intermediate and a versatile chiral building block in organic synthesis. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) agents, receptor ligands, and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bespoke alkaloids and potential drug candidates targeting neurological pathways.
• Chiral Catalyst or Ligand: Utilized in asymmetric synthesis due to its rigid, defined stereochemistry at the 5 and 11 positions.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool Compound: Employed in pharmacological research to study receptor interactions and enzyme inhibition.
• Advanced Organic Synthesis: Building block for constructing complex polycyclic molecular architectures in academic and industrial R&D.

Basic Information

Product Name	(5S,11S)-5,6,11,12-Tetrahydro-2,3,8,9-Tetramethoxy-5,11-Epiminodibenzo[A,E]Cyclooctene
CAS No.	529-79-3
Molecular Formula	C20H23NO4
Molecular Weight	341.40 g/mol
Synonyms	(-)-Corytuberine; (5S,11S)-5,6,11,12-Tetrahydro-2,3,8,9-tetramethoxydibenzo[a,e]cycloocten-5,11-imine; NSC 51046; L-Corytuberine; 5,11-Epiminodibenzo[a,e]cyclooctene, 5,6,11,12-tetrahydro-2,3,8,9-tetramethoxy-, (5S,11S)-; Corytuberine
EINECS	208-463-9

Quality Control

We supply (5S,11S)-5,6,11,12-Tetrahydro-2,3,8,9-Tetramethoxy-5,11-Epiminodibenzo[A,E]Cyclooctene in high-purity grades suitable for research and development. Our products undergo rigorous quality testing including HPLC, NMR, and chiral purity analysis to ensure identity, potency, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.